While its benefits are well-understood, with hundreds of supplements featuring L-citrulline, some people may experience concerning side effects. We’re here to explain so you can be aware before taking it.
WHAT ARE THE RISKS?
L-Citrulline provides an edge to athletes by increasing blood flow to muscles, improving workout “pump.” However, for some people the side effects can be dangerous.
By dilating blood vessels and increasing nitric oxide, L-citrulline actually lowers overall blood pressure. While this can be helpful for users with prehypertension, some people already have low blood pressure, and further reduction can be harmful.
Another possible risk of L-citrulline is its effects on the kidneys. While it doesn’t cause direct harm, L-citrulline can increase overall creatine levels.
Creatine is widely taken to boost muscle recovery, but research shows that for some, too much creatine can actually harm kidney function or cause upset stomach.
If you have low blood pressure or a condition affecting the kidneys, L-citrulline could cause serious problems. Your doctor can help you make the correct choices about usage or suggest an alternative.
On the flip side, some individuals might actually benefit from lowered blood pressure and creatine, like athletes with high blood pressure who don’t have issues with creatine.
Our final warning about L-citrulline concerns dosage and applies to all supplements. Large doses of L-citrulline can cause intestinal issues. Make sure not to exceed the recommended dosages of your supplements.
If you’re taking citrulline on its own, experts recommend a maximum of 1000 mg L-citrulline daily for safety.
For the majority of users, L-citrulline is completely safe. It’s well-studied, all-natural, and widely used. However, those with pre-existing conditions should be aware of the possible side effects.