ForsLean is a standardized extract of a substance called forskolin found exclusively in the roots of coleus forskohlii, a tropical perennial plant.
Forskolin has been used since ancient times to treat heart and respiratory disorders, but was only recently patented and distributed by Sabinsa Corporation. Forskolin strengthens heartbeat and widens blood vessels, thereby lowering blood pressure. It is also used to treat various conditions, such as allergies, obesity, bladder infections, and cancer.
Through its effect on cAMP, ForsLean may increase basal metabolic rate and utilization of body fat. This improves lean body mass, or the fat-to-muscle ratio in the body.
There is also some evidence that forskolin lowers appetite and thus reduces food intake.
ForsLean may mitigate other effects of obesity as well. In one unpublished study conducted in Japan, ForsLean decreased body fat, improved BMI, and preserved lean body mass without adverse effects, including no significant change in blood pressure.
In another study, 23 females who supplemented their diet with ForsLean decreased gains in body mass, but no significant differences in body fat were found. The subjects did report less fatigue and hunger, with no significant side effects.
Oral ingestion of forskolin for twelve weeks also decreased body fat percentage and fat mass in overweight men, along with increasing bone mass and serum free testosterone levels.
However, combining coleus forskohlii with blood-pressure medications and blood thinners may prove unsafe. Consequently, people using these medications should consult a doctor before using ForsLean. In addition, people with gastric ulcers or low blood pressure should avoid using ForsLean.
Supplements containing coleus forskohlii, similar to ForsLean, were linked to four cases of poisoning in Italy in 2005. Authorities suspected the coleus forskohlii used had been contaminated by a poisonous plant, but this danger isn’t typical of ForsLean.
 “ForsLean.” ForsLean.com. © Sabinsa Corporation 2011.
 “Effects of Coleus Forskohlii Supplementation on Body Composition and Hematological Profiles in Mildly Overweight Women.” Journal of the International Society of Sports Nutrition. 2005; 2 (2): 54-62.
 Michael P. Godard et al.“Body Composition and Hormonal Adaptations with Forskolin Consumption in Overweight and Obese Men.” Obesity Research. 2005; 13 (8): 1335-1343.
 “Coleus forskohlii.” NYU Langone Medical Center. 2013 EBSCO Publishing.
 “Contaminated coleus forskohlii products cause adverse reactions in Italy.” NutraIngredients.com. 1 June 2005.