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Caffeine Anhydrous

    Caffeine anhydrous is the dehydrated caffeine form that occurs naturally in plants such as coffee beans and tea leaves.

    Liquid caffeine is drawn from plant sources. This liquid is then boiled until the water is evaporated. This process produces caffeine anhydrous, a white, crystalline powder. This powder has 0.5% or less water and is meant to be consumed with food or liquid. It is odorless, bitter, and highly concentrated.[1]

    Caffeine anhydrous is sold alone as an energy booster, workout enhancer, and fat burner. The powder is also compressed into tablets to be taken as exercise supplements or caffeine pills.

    Caffeine anhydrous’ main benefit compared to conventional caffeine forms is convenience. The concentrated nature allows for high caffeine content in small doses.

    One-sixteenth of a teaspoon caffeine anhydrous powder contains 168 mg caffeine.[2] Typical caffeine pills contain 200 mg caffeine.[3] In comparison, a cup of coffee only contains 100-200 mg.[4]

    Caffeine also enhances sport performance in low-to-moderate doses. Caffeine anhydrous is more effective and faster at enhancing performance than drinking coffee or other caffeinated beverages.[5] The greatest performance enhancement is to endurance in aerobic activity, with less-pronounced increase in upper-body strength and weight training.[5]

    Furthermore, consuming caffeine anhydrous has the same effect on mental alertness as caffeine in liquid form. It stimulates dopamine and serotonin levels, resulting in a feeling of well-being.[6]

    An additional caffeine benefit includes increased energy. As caffeine binds to adenosine receptors, it prevents adenosine from halting neural activity. Without active adenosine receptors, the body acts as though more energy is available, reducing fatigue. The pituitary gland reacts by instructing the adrenal glands to produce adrenaline, giving a boost of extra energy.[7]

    Caffeine also acts as a mild diuretic when taken after a period of caffeine deprivation. This water loss through urination assists in short-term weight loss. However, a tolerance is quickly developed, and urination returns to normal.[8]

    Finally, caffeine acts as a mild appetite suppressant.[9]

    In proper amounts, caffeine anhydrous is considered safe.

    Side effects of large doses can include:[10]

    • Insomnia
    • Headache
    • Chest Pain
    • Agitation
    • Irregular or elevated heart rate

    Individuals with the following conditions should not consume large amounts of caffeine:[11]

    • Pregnant or breastfeeding
    • High blood pressure
    • Diabetes[10]
    • Depression
    • Anxiety disorders

    Safe amounts vary according to weight, body type, and age, but consuming more than 300 mg in a short time period is not recommended.[12] Experts agree 600 mg caffeine or more each day is too much.[13]

    However, for optimal performance enhancement, an individual should take 3-5 mg caffeine anhydrous per kg body weight before exercising to increase stamina and endurance. Doses larger than 6 mg/kg do not result in greater athletic performance.[5]

    • [1] Ash, Irene. “Handbook of Fillers, Extenders, and Diluents”; 2007. 35.
    • [2] True Nutrition. “Caffeine Anhydrous Powder.”
    • [3] Drugs.com. “ALVA 200 mg.”
    • [4] DeNoon, Daniel “How Much Caffeine Is in Your Energy Drink?” WebMD.
    • [5] Goldstein, Erica R et. Al. “International society of sports nutrition position stand: caffeine and performance.” Journal of the International Society of Sports Nutrition. 27.7 (2010): 5.
    • [6] Franklin, Jon “Benefits of Caffeine Anhydrous for Pre-Workout.” Pre-Workout Buzz.
    • [7] “What Caffeine Actually Does to Your Brain.” Lifehacker.
    • [8] Maughan, RJ and Griffin, J. “Caffeine ingestion and fluid balance: a review.” Journal of Human Nutrition and Dietetics. 16.6 (2003): 411.
    • [9] Zeratsky, Katherine “Does caffeine help with weight loss?” Mayo Clinic.
    • [10] WebMD. “Caffeine.”
    • [11] Drugs.com. “Caffeine side effects.”
    • [12] Caffeineanhydrousinfo.org. “Side Effects and Risks.”
    • [13] U.S. Food and Drug Administration. “Medicines in my Home: Caffeine and Your Body.” (2007): 2

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