African mango, or irvingia gabonensis, is a superfruit used to manage weight and relieve some symptoms of metabolic syndrome . It is commonly grown in the humid forest zones of Angola, Congo, Nigeria, and Uganda.
African mango is similar to an ordinary mango in that the fruit can be eaten raw or processed into jams, jelly, or juices. However, it is primarily studied for its fiber-rich seed, or dika nut, rather than the fruit.
In supplements, African mango seed extract is used to do the following:
- Increase Metabolism
- Lower Cholesterol
- Manage Diabetes
- Eliminate Toxins
- Improve Digestion
Some studies suggest African mango manipulates adiponectin and leptin levels. Adiponectin is a protein hormone that regulates glucose and plays a role in processing fatty acids. Leptin, on the other hand, is a similar hormone which regulates energy intake and expenditure, including appetite and metabolism. By regulating these two hormones, African mango extract improves body composition and other metabolic factors.
African mango’s high-fiber content also has an impact on cholesterol levels. As the fiber moves through the body, it inhibits cholesterol absorption while promoting its removal from the blood stream.
African mango studies reveal that its natural fiber triggers improvements to body weight, body fat, and waist circumference.
In a study using a patented form of African mango extract, known as IGOB131, researchers found irvingia gabonensis supplementation before meals improved fasting lipids, blood glucose, adiponectin, and leptin levels. Together, these metabolic parameters resulted in significant weight loss over the course of 10 weeks.
Additional African mango studies suggest African mango is an effective tool for counteracting obesity by regulating specific hormones.
A validated experimental model suggested African mango seed extract “inhibits adipogenesis through modulation of PPAR gamma and glycerol-3-phosphate dehydrogenase in addition to the beneficial impact upon leptin and adiponectin.”
While no studies have been conducted to determine the effects of taking African mango over a long period of time, validated research has shown that taking African mango for up to 10 weeks is safe.
A few users reported headache, dry mouth, gastrointestinal complaints, difficulty sleeping, and flu-like symptoms.
African mango has not been tested for drug interactions, so information is limited. Theoretically, African mango may increase side effects caused by diabetes and cholesterol medication. This is because African mango has a direct impact on blood sugar levels and cholesterol absorption.
African mango also delays gastric emptying, so prescription medications should be used with caution.
Information regarding safety and efficacy in pregnancy and lactation is lacking. If you are pregnant or nursing, do not take African mango.
Clinical studies used standardized 150 mg dosages taken 30 minutes before lunch and dinner. Or, 1,050 mg of crude seed extract divided into 3 doses daily, 30 minutes before meals with a glass of warm water.
The most common supplement regimens consist of 150 mg African mango twice daily with food.
-  “Dr. Oz Recent Affirmation That African Mango is an Effective Weight Loss Supplement Coincides With New Supplement From Bel Marra Nutritionals.” PRWeb. March 11, 2013.
-  Judith L Ngondi, Blanche C Etoundi, Christine B Nyangono, Carl MF Mbofung, and Julius E Oben. “IGOB131, a novel seed extract of the West African plant Irvingia gabonensis, significantly reduces body weight and improves metabolic parameters in overweight humans in a randomized double-blind placebo controlled investigation.” Lipids Health Dis. 2009; 8: 7. Published online 2009 March 2. doi: 10.1186/1476-511X-8-7.
-  Oben J, Ngondi JL, Blum K. “Inhibition of Irvingia gabonensis seed extract (OB131) on adipogenesis as mediated via down regulation of the PPARy and Leptin genes and up-regulation of the adiponectic gene.” Lipids in Health and Disease. 2008;7:44. doi: 10.1186/1476-511X-7-44.
-  “Irvingia Gabonensis.” WebMD.
-  “African Mango.” Drugs.com.