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2022's 10 Best
Butterbur Supplements

Butterbur, which is also known as Petasites hybridus, is a marsh shrub plant that grows in Asia, Europe, and North America. It is a member of the sunflower family and related to plants such as the marigold and dandelion. Butterbur blooms with pink, green, or white flowers. The plant has large leaves which are often used to wrap and preserve butter when the weather is warm— a use to which butterbur owes its name.


Butterbur has been used for many years for medicinal purposes. Its uses date back as far as the middle ages where it was used to treat the plague and fevers. In the 17th century, it was also used to treat skin wounds, coughs, and asthma. To this day, butterbur is still used for its many medicinal benefits.


Butterbur is also available as a supplement that contains processed extracts from the leaves, root, or stem. Butterbur supplements offer a number of great benefits. Let’s take a closer look at them.



The Benefits of Butterbur Supplements


TREATS SEASONAL ALLERGIES

Butterbur can effectively treat symptoms of seasonal hay fever allergies. Aw, man, do I wish I had known that twenty years ago. You’re probably familiar with the symptoms, but they may include watery and itchy eyes, as well as sneezing. Butterbur is recognized as a natural alternative to commonly-used synthetic allergy medications. It could even replace antihistamines and steroids.

A study was performed which assessed the effect of butterbur on those with allergic rhinitis symptoms (seasonal allergies). The efficiency of butterbur was tested against a placebo, and the allergy medication Fexofenadine. The study revealed that butterbur could significantly reduce the symptoms of seasonal allergies. Even more promising, butterbur produced identical results to those of the Fexofenadine medication.

TREATS MIGRAINES

Migraines can produce debilitating symptoms. I know this one pretty well too. Symptoms include pain, dizziness, nausea, sensitivity to light, sensitivity to sound, and even vomiting. Butterbur is a proven natural migraine remedy. It can also be used to reduce the frequency of migraines long-term, as one study showed. The study was performed on 245 patients that were each given 50mg or 75mg doses of butterbur or a placebo. The 50mg dose was no more effective than the placebo. However, the 75mg dose reduced migraine frequency in patients by 48% over four months.

In another study, the effects of butterbur in the form of the product Petadolex were assessed on migraine symptoms against a placebo. The study revealed that the butterbur supplement reduced the frequency of migraine attacks in patients by over 60%. All this demonstrates that butterbur is an effective natural treatment for migraines. Jump to Our 10 Best Butterbur Supplement List

PROTECTS THE BRAIN

A surprising but promising benefit of butterbur is that it may have the ability to protect the brain against harmful free radicals.

Free radicals are compounds that develop due to environmental factors that cause a state of stress in the body such as poor diet and pollution. Antioxidants neutralize free radicals and limit the potential oxidative damage. Oxidative damage can lead to cell damage which can eventually cause chronic disease.

A study performed on mice tested the efficacy of butterbur for protection against oxidative damage to the brain. The damage was induced and caused by the administration of the neurotoxin kainic acid. The study revealed that butterbur remarkably reduced the symptoms of toxicity in the mice. Butterbur therefore may be an effective agent in protecting the brain against oxidative damage.

Kaempferol is a plant compound found in butterbur. It is also found in foods such as spinach, broccoli, green tea, and apples. Studies show that kaempferol can protect and prevent against oxidative stress. Even more promising, it may also be able to prevent and treat neurodegenerative diseases such as dementia and Alzheimer’s.

PROTECTS THE HEART

Oxidative damage is not just limited to the brain. Antioxidants can also protect the heart and reduce the risk of heart disease.

A 2010 study tested the effect of butterbur supplementation on oxidative stress and bad LDL cholesterol in mice. The study revealed that butterbur decreased bad cholesterol. It also reduced oxidative stress by regulating antioxidant enzymes.

Thanks to the component kaempferol found in butterbur, it may also be able to protect against heart damage caused by heart attacks. A 2008 study showed that kaempferol could offer protection against cardiac dysfunction.





IMPROVES ASTHMA SYMPTOMS

Asthma is a common respiratory condition. It affects millions of people and can even cause death. Some promising studies have shown that butterbur may be able to reduce symptoms of asthma when used in combination with traditional medical treatments.

A 2004 study tested butterbur root extract as a treatment for asthma on 80 individuals. Butterbur extract supplements were taken for two months. These two months were then followed by a two-month period of optional supplementation. Regular asthma medication was permitted during the study. Results showed that participants experienced shorter, less frequent, and less severe asthma attacks following the consumption of butterbur supplements. It also helped to improve their peak flow level and forced expiratory volume (FEV1). Even more promising, 40% of patients who were using asthma medications were able to reduce their doses by the end of the study.

Butterbur can be used in conjunction with other medical treatments for asthma. In some cases, it may also be used as the sole treatment for the symptoms of this condition. Butterbur could help to reduce the symptoms and severity of asthma. It could also reduce the frequency of asthma attacks.

DECREASES BODY FAT

Butterbur may have the ability to reduce body fat. A study was performed using mice with diet-induced obesity. The study revealed that butterbur extract was effective in lowering visceral fat tissue accumulation and body weight gain. High body fat levels can lead to obesity and many health conditions including heart disease and diabetes. Butterbur may have the ability to promote fat loss in humans and thus reduce the risk of such conditions.

DECREASES INFLAMMATION

Chronic inflammation is an immune response and the primary cause of many diseases. It is also a contributing factor to conditions such as cancer, diabetes, obesity, and heart disease. Reducing inflammation can help to protect against disease. Studies show that the component kaempferol in butterbur can effectively reduce inflammatory markers in mice and reduce oxidative stress.


Butterbur Side Effects and Considerations


Most individuals tolerate butterbur supplements well. However, those with allergies to plants in the Asteraceae/Compositae family, such as daisies and marigolds, may experience allergy symptoms upon consumption of this herb. Allergy symptoms may include itching, watering eyes, and swelling of the throat. If you experience any negative symptoms, stop taking the product immediately. In the case of an emergency, seek medical advice.

Although usually safe to consume, butterbur may cause side effects in some people. These symptoms may include itchy eyes, headaches, fatigue, and digestive issues such as diarrhea.

It is not yet known if butterbur is safe to use during pregnancy. For this reason, it is advised that you avoid this supplement if you are pregnant or breastfeeding.

If you have any health conditions or are taking medication, you may wish to consult with your doctor before taking butterbur supplements. Jump to Our 10 Best Butterbur Supplement List



What to Look for when Buying Butterbur Supplements


Butterbur is available in capsule form and also as a dried extract in the form of a tea. Some butterbur supplements contain other natural ingredients. These multiple-ingredient products are typically intended to treat specific complaints such as migraines or allergies.

As butterbur is a natural supplement, look for a product with the least amount of added artificial ingredients. This will ensure maximum strength, purity, and quality.

Raw and unprocessed butterbur contains chemical pyrrolizidine alkaloids. These chemicals can be dangerous, especially for those with liver problems. Always ensure that the product you are using contains a processed extract of butterbur and that it is labeled as certified PA-free.


Dosage for Butterbur Supplements


Most supplements have dosage guidelines on the label. Studies show that the most effective dose of butterbur is a twice-daily dose of 50-75mg.

It is advisable to start with the minimum dose and follow the instructions on the bottle. This will allow time to assess your tolerance to the supplement. Increase the dose if and when you find it necessary to do so. Do this gradually to prevent unwanted side effects. Do not exceed the maximum dose as stated on the label.


Conclusion


Butterbur supplements provide a range of health benefits. As a supplement, it could help to protect the heart and the brain against harmful oxidative damage. Butterbur also shows promising evidence as a natural alternative to seasonal allergy medication. If you’ve decided that butterbur is for you, check out our top 10 butterbur supplements below.


References

  1. Erica Cirino Butterbur for Allergies HealthLine.com
  2. National Center for Complementary and Integrative Health Butterbur PubMed.gov
  3. Rachael Link, MS, RD Butterbur: The Herb that Relieves Allergies, Migraines & More DrAxe.com
  4. Schapowal, A. Treating Intermittent Allergic Rhinitis: A Prospective, Randomized, Placebo and Antihistamine-Controlled Study of Butterbur Extract Ze 339 PubMed.gov
  5. Lipton, R.B., Göbel, H., Einhäupl, K.M., Wilks, K,, Mauskop, A. Petasites Hybridus Root (Butterbur) is an Effective Preventive Treatment for Migraine PubMed.gov
  6. Grossman, W., Schmidramsl, H. An Extract of Petasites Hybridus is Effective in the Prophylaxis of Migraine PubMed.gov
  7. Danesch, U.C. Petasites Hybridus (Butterbur Root) Extract in the Treatment of Asthma–An Open Trial PubMed.gov
  8. Sok, D.E., Oh, S.H., Kim, Y.B., Kang, H.G., Kim, M.R. Neuroprotection by Extract of Petasites Japonicus Leaves, A Traditional Vegetable, Against Oxidative Stress in Brain of Mice Challenged with Kainic Acid PubMed.gov
  9. Yang, E.J., Kim, G.S., Jun, M., Song, K.S. Kaempferol Attenuates the Glutamate-Induced Oxidative Stress in Mouse-Derived Hippocampal Neuronal HT22 Cells PubMed.gov
  10. Park, C.H., Kim, M.Y., Sok, D.E., Kim, J.H., Lee, J.H., Kim, M.R. Butterbur (Petasites Japonicus Max.) Extract Improves Lipid Profiles and Antioxidant Activities in Monosodium L-Glutamate-Challenged Mice PubMed.gov
  11. Qi-Sheng Yang, Li-Ping He, Xian-Long Zhou, Yan Zhao, Jun Shen, Peng Xu, and Shao-Zhou Ni Kaempferol Pretreatment Modulates Systemic Inflammation and Oxidative Stress Following Hemorrhagic Shock in Mice PubMed.gov
  12. Watanabe, T., Hata, K., Hiwatashi, K., Hori, K., Suzuki, N., Itoh, H. Suppression of Murine Preadipocyte Differentiation and Reduction of Visceral Fat Accumulation by a Petasites Japonicus Ethanol Extract in Mice Fed a High-Fat Diet PubMed.gov
  13. WebMD Butterbur WebMD.com

#1 - Butterbur

Nutricost’s Butterbur Extract is our number one supplement for its great quality and price. There are 120 capsules per container, and butterbur is the sole ingredient. This product is non-GMO and gluten-free and contains absolutely no added ingredients. This supplement can help to relieve spasms caused by migraines.

  • 120 capsules per bottle
  • 75mg of butterbur per serving
  • Gluten free
  • Non-GMO
Keep Reading »

Nutricost’s Butterbur Extract is our number one supplement for its great quality and price. There are 120 capsules per container, and butterbur is the sole ingredient. This product is non-GMO and gluten-free and contains absolutely no added ingredients. This supplement can help to relieve spasms caused by migraines.

  • 120 capsules per bottle
  • 75mg of butterbur per serving
  • Gluten free
  • Non-GMO
Keep Reading »

#2 - Bulk Supplements Butterbur Extract Powder

Butterbur Extract Powder by Bulk Supplements is a powder supplement with butterbur as the sole ingredient. Each packet has 66 servings, and each serving contains 150mg of butterbur. This supplement is free of dairy, sugar, gluten, soy, yeast, and additives and may be effective at relieving the symptoms of seasonal allergies.

  • 66 servings per packet
  • 150mg of butterbur extract per serving
  • No added ingredients
  • Natural and free of preservatives
Keep Reading »

Butterbur Extract Powder by Bulk Supplements is a powder supplement with butterbur as the sole ingredient. Each packet has 66 servings, and each serving contains 150mg of butterbur. This supplement is free of dairy, sugar, gluten, soy, yeast, and additives and may be effective at relieving the symptoms of seasonal allergies.

  • 66 servings per packet
  • 150mg of butterbur extract per serving
  • No added ingredients
  • Natural and free of preservatives
Keep Reading »

#3 - NOW Foods Butterbur

NOW Foods’ Butterbur with feverfew capsules may support healthy blood flow to the brain. This product is free from wheat, gluten, milk, soy, egg, and fish. NOW Foods is a reputable family-owned brand, and all of their products are made in the USA and Canada. NOW Foods products are tested in accordance with GMP in-house in their own facilities to ensure quality.

  • 60 servings per container
  • 75mg of butterbur extract per serving
  • Manufactured and tested in the USA and Canada to GMP standards
Keep Reading »

NOW Foods’ Butterbur with feverfew capsules may support healthy blood flow to the brain. This product is free from wheat, gluten, milk, soy, egg, and fish. NOW Foods is a reputable family-owned brand, and all of their products are made in the USA and Canada. NOW Foods products are tested in accordance with GMP in-house in their own facilities to ensure quality.

  • 60 servings per container
  • 75mg of butterbur extract per serving
  • Manufactured and tested in the USA and Canada to GMP standards
Keep Reading »

#4 - LES Labs Sinus & Seasonal

LES Labs Sinus and Seasonal capsules contain a cocktail of natural ingredients. These ingredients include quercetin, stinging nettle root extract, bromelain, butterbur extract, and black pepper fruit extract. This supplement is marketed as a natural formula for those with sinus problems and seasonal allergies. LES Labs supplements are backed by a 60-day money-back guarantee and their supplements are manufactured in the USA.

  • 60 servings per container
  • 50mg of butterbur root extract per capsule
  • Natural and free of preservatives
  • 60-day money back guarantee
  • Manufactured in the USA
Keep Reading »

LES Labs Sinus and Seasonal capsules contain a cocktail of natural ingredients. These ingredients include quercetin, stinging nettle root extract, bromelain, butterbur extract, and black pepper fruit extract. This supplement is marketed as a natural formula for those with sinus problems and seasonal allergies. LES Labs supplements are backed by a 60-day money-back guarantee and their supplements are manufactured in the USA.

  • 60 servings per container
  • 50mg of butterbur root extract per capsule
  • Natural and free of preservatives
  • 60-day money back guarantee
  • Manufactured in the USA
Keep Reading »

#5 - Vita Science Migravent

Migravent softgels by Vita contain clinically-studied ingredients that may help to reduce the occurrence and severity of migraines. Migravent contains butterbur, CoQ10, magnesium, and riboflavin in a single capsule. The butterbur extract in this supplement is tested by an independent third-party laboratory to ensure the absence of harmful pyrrolizidine alkaloids. Migravent is manufactured in the United States in a GMP-certified facility.

  • 60 softgels per container
  • May be helpful in treating migraines
  • Tested for safety in a third party-laboratory
  • Manufactured in a GMP-certified facility in the USA
Keep Reading »

Migravent softgels by Vita contain clinically-studied ingredients that may help to reduce the occurrence and severity of migraines. Migravent contains butterbur, CoQ10, magnesium, and riboflavin in a single capsule. The butterbur extract in this supplement is tested by an independent third-party laboratory to ensure the absence of harmful pyrrolizidine alkaloids. Migravent is manufactured in the United States in a GMP-certified facility.

  • 60 softgels per container
  • May be helpful in treating migraines
  • Tested for safety in a third party-laboratory
  • Manufactured in a GMP-certified facility in the USA
Keep Reading »

#6 - Linpharma Petadolex

Petadolex by Linpharma is effective at treating migraines and is the brand that is commonly used in medical research. Petadolex supplements are made in Germany and use a process which is patented for the removal of the PA toxins that are naturally found in raw butterbur. Petadolex has been a trusted brand since 1972.

  • 60 servings per container
  • 75mg of butterbur extract per serving
  • Patented product
  • Made in Germany
Keep Reading »

Petadolex by Linpharma is effective at treating migraines and is the brand that is commonly used in medical research. Petadolex supplements are made in Germany and use a process which is patented for the removal of the PA toxins that are naturally found in raw butterbur. Petadolex has been a trusted brand since 1972.

  • 60 servings per container
  • 75mg of butterbur extract per serving
  • Patented product
  • Made in Germany
Keep Reading »

#7 - Vitacost Butterbur

Butterbur Extract by Vitacost contains 75mg per serving and 120 capsules per container. This supplement is free from milk, gluten, peanuts, eggs, fish, soy, and titanium dioxide. All Vitacost supplements are produced in accordance with the Current Good Manufacturing Practices.

  • 120 capsules per container
  • 75mg of butterbur extract per serving
  • Manufactured in accordance with the CGMP
Keep Reading »

Butterbur Extract by Vitacost contains 75mg per serving and 120 capsules per container. This supplement is free from milk, gluten, peanuts, eggs, fish, soy, and titanium dioxide. All Vitacost supplements are produced in accordance with the Current Good Manufacturing Practices.

  • 120 capsules per container
  • 75mg of butterbur extract per serving
  • Manufactured in accordance with the CGMP
Keep Reading »

#8 - Source Naturals Butterbur

Source Naturals is a reputable brand in the natural supplement industry. Their butterbur extract softgels contain 50mg of butterbur root extract per serving. This supplement is free from dairy, yeast, gluten, egg, soy, wheat, and corn. This product supports healthy bladder function, is available in a range of sizes, and is great value for money.

  • 50mg of butterbur extract per serving
  • Supports healthy bladder function
Keep Reading »

Source Naturals is a reputable brand in the natural supplement industry. Their butterbur extract softgels contain 50mg of butterbur root extract per serving. This supplement is free from dairy, yeast, gluten, egg, soy, wheat, and corn. This product supports healthy bladder function, is available in a range of sizes, and is great value for money.

  • 50mg of butterbur extract per serving
  • Supports healthy bladder function
Keep Reading »

#9 - Carlyle Butterbur

Butterbur extract by Carlyle is great value for money and contains 120 capsules per bottle. All Carlyle supplements are packaged and lab-tested in the USA and are manufactured in an FDA-registered facility in accordance with the Good Manufacturing Practices.

  • 120 capsules per bottle
  • 75mg of butterbur per serving
  • Manufactured in the USA in accordance with the GMP
Keep Reading »

Butterbur extract by Carlyle is great value for money and contains 120 capsules per bottle. All Carlyle supplements are packaged and lab-tested in the USA and are manufactured in an FDA-registered facility in accordance with the Good Manufacturing Practices.

  • 120 capsules per bottle
  • 75mg of butterbur per serving
  • Manufactured in the USA in accordance with the GMP
Keep Reading »

#10 - Nature's Nectar Mind Ease

Mind Ease by Nature’s Nectar can provide relief from migraines. This supplement contains all-natural and scientifically-backed ingredients. These ingredients include butterbur root, feverfew extract, and riboflavin (Vitamin B2). This product is backed by a 100% satisfaction money-back guarantee. All Nature’s Nectar products are produced in FDA-approved facilities in the United States in accordance with GMP.

  • 60 capsules per container
  • 150mg of butterbur root extract per serving
  • All-natural ingredients
  • Money-back guarantee
  • Manufactured in the USA in accordance with GMP
Keep Reading »

Mind Ease by Nature’s Nectar can provide relief from migraines. This supplement contains all-natural and scientifically-backed ingredients. These ingredients include butterbur root, feverfew extract, and riboflavin (Vitamin B2). This product is backed by a 100% satisfaction money-back guarantee. All Nature’s Nectar products are produced in FDA-approved facilities in the United States in accordance with GMP.

  • 60 capsules per container
  • 150mg of butterbur root extract per serving
  • All-natural ingredients
  • Money-back guarantee
  • Manufactured in the USA in accordance with GMP
Keep Reading »

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